Biomaterials and emerging anticancer therapeutics: engineering the microenvironment

  title={Biomaterials and emerging anticancer therapeutics: engineering the microenvironment},
  author={Luo Gu and David J Mooney},
  journal={Nature Reviews Cancer},
The microenvironment is increasingly recognized to have key roles in cancer, and biomaterials provide a means to engineer microenvironments both in vitro and in vivo to study and manipulate cancer. In vitro cancer models using 3D matrices recapitulate key elements of the tumour microenvironment and have revealed new aspects of cancer biology. Cancer vaccines based on some of the same biomaterials have, in parallel, allowed for the engineering of durable prophylactic and therapeutic anticancer… CONTINUE READING
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