Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes.

@article{Gorbet2004BiomaterialassociatedTR,
  title={Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes.},
  author={Maud Gorbet and Michael Vivian Sefton},
  journal={Biomaterials},
  year={2004},
  volume={25 26},
  pages={5681-703}
}
Our failure to produce truly non-thrombogenic materials may reflect a failure to fully understand the mechanisms of biomaterial-associated thrombosis. The community has focused on minimizing coagulation or minimizing platelet adhesion and activation. We have infrequently considered the interactions between the two although we are generally familiar with these interactions. However, we have rarely considered in the context of biomaterial-associated thrombosis the other major players in blood… CONTINUE READING
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