Biomarkers reflect differences in osteoarthritis phenotypes of the lumbar spine: the Johnston County Osteoarthritis Project.

@article{Goode2017BiomarkersRD,
  title={Biomarkers reflect differences in osteoarthritis phenotypes of the lumbar spine: the Johnston County Osteoarthritis Project.},
  author={Adam Goode and Amanda E. Nelson and Virginia B. Kraus and Jordan B. Renner and Joanne M. Jordan},
  journal={Osteoarthritis and cartilage},
  year={2017},
  volume={25 10},
  pages={
          1672-1679
        }
}
OBJECTIVE To determine differences in biomarker levels between radiographic phenotypes of facet joint osteoarthritis (FOA) only, spine OA only ((disc space narrowing (DSN) and vertebral osteophytes (OST)) or the combination of FOA and spine OA. DESIGN A cross-sectional analysis of data from 555 participants in the Johnston County Osteoarthritis Project was performed. Lumbar spine levels were graded by severity (OST and DSN) and presence (FOA) of degeneration. Biomarkers included hyaluronan… CONTINUE READING
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