Biomarkers of the Tumor Microenvironment

@inproceedings{Akslen2017BiomarkersOT,
  title={Biomarkers of the Tumor Microenvironment},
  author={Lars A. Akslen and Randolph S. Watnick},
  booktitle={Springer International Publishing},
  year={2017}
}
The tumor microenvironment plays a crucial role in cancer development and progression. Paracrine signaling between tumor cells and the nonneoplastic, genetically normal, cells that make up the microenvironment is a critical component influencing the progression of tumors from the in situ stage to metastatic disease. Despite the importance of these paracrine signaling mechanisms and factors, the vast majority of academic research and development in the pharmaceutical industry is still targeted… CONTINUE READING

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