Biomarkers of multiorgan injury in a preclinical model of exertional heat stroke.

@article{King2015BiomarkersOM,
  title={Biomarkers of multiorgan injury in a preclinical model of exertional heat stroke.},
  author={M. King and L. Leon and Danielle L. Mustico and Joel M. Haines and T. Clanton},
  journal={Journal of applied physiology},
  year={2015},
  volume={118 10},
  pages={
          1207-20
        }
}
It is likely that the pathophysiology of exertional heat stroke (EHS) differs from passive heat stroke (PHS), but this has been difficult to verify experimentally. C57Bl/6 mice were instrumented with temperature transponders and underwent 3 wk of training using voluntary and forced running wheels. An EHS group was exposed to environmental temperatures (Tenv) of 37.5, 38.5, or 39.5°C at either 30, 50, or 90% relative humidities (RH) while exercising on a forced running wheel. Results were… Expand
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References

SHOWING 1-10 OF 78 REFERENCES
Cardiovascular and thermoregulatory biomarkers of heat stroke severity in a conscious rat model.
  • 27
  • PDF
Heat stress induces a biphasic thermoregulatory response in mice.
  • 110
  • PDF
Rat model of acute heatstroke mortality.
  • 125
Role of physical effort in the etiology of rat heatstroke injury and mortality.
  • 28
Diagnostic significance of selected serum enzymes in a rat heatstroke model.
  • 19
  • Highly Influential
Heatstroke during endurance exercise: is there evidence for excessive endothermy?
  • 42
Heat stroke and cytokines.
  • L. Leon
  • Medicine
  • Progress in brain research
  • 2007
  • 102
Protection of intestinal injury during heat stroke in mice by interleukin‐6 pretreatment
  • 34
Acute exercises induce disorders of the gastrointestinal integrity in a murine model
  • 9
Time course of cytokine, corticosterone, and tissue injury responses in mice during heat strain recovery.
  • 126
  • PDF
...
1
2
3
4
5
...