Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms?

@article{Golightly2011BiomarkersOI,
  title={Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms?},
  author={Yvonne M. Golightly and Stephen William Marshall and Virginia B. Kraus and Jordan B. Renner and Andr{\'e}s Villaveces and Carri H. Casteel and Joanne M. Jordan},
  journal={Arthritis and rheumatism},
  year={2011},
  volume={63 8},
  pages={2276-83}
}
OBJECTIVE To explore the ability of osteoarthritis (OA)-related biomarkers to predict incident radiographic knee OA in a large sample of African American and Caucasian men and women. METHODS Baseline levels of serum cartilage oligomeric matrix protein (COMP), hyaluronan (HA), high-sensitivity C-reactive protein (hsCRP), and keratan sulfate (KS) and baseline and followup radiographs were available for 353 knees without baseline osteophyte formation and for 446 knees without baseline joint… CONTINUE READING