Biomarkers of cardiovascular damage and dysfunction--an overview.

  title={Biomarkers of cardiovascular damage and dysfunction--an overview.},
  author={Paul O. Collinson and David C. Gaze},
  journal={Heart, lung & circulation},
  volume={16 Suppl 3},
Acute coronary syndromes (ACS) are due to the rupture or erosion of atheromatous plaques. This produces, depending on plaque size, vascular anatomy and degree of collateral circulation, progressive tissue ischaemia which may progress to cardiomyocyte necrosis and subsequent cardiac remodelling. Cardiac biomarkers can be used for diagnosis and assessment of all of these stages. Markers to detect myocardial ischaemia at the pre-infarction stage are potentially the most interesting but also the… CONTINUE READING