Biomarkers of aggressive pituitary adenomas.

  title={Biomarkers of aggressive pituitary adenomas.},
  author={Ozgur Mete and Shereen Ezzat and Sylvia L Asa},
  journal={Journal of molecular endocrinology},
  volume={49 2},
Pituitary adenomas exhibit a wide range of behaviors. The prediction of aggressive or malignant behavior in pituitary adenomas remains challenging; however, the utility of biomarkers is rapidly evolving. In this review, we discuss potential biomarkers as they relate to aggressive behavior in pituitary adenomas. While detailed histological subtyping remains the best independent predictor of aggressive behavior in the majority of cases, evidence suggests that the additional analyses of FGFR4, MMP… CONTINUE READING