Biomarkers of AAA progression. Part 1: extracellular matrix degeneration

  title={Biomarkers of AAA progression. Part 1: extracellular matrix degeneration},
  author={Femke A. M. V. I. Hellenthal and Willem A. Buurman and Will K. W. H. Wodzig and Geert Willem H. Schurink},
  journal={Nature Reviews Cardiology},
Abdominal aortic aneurysm (AAA) is an important health problem. Elective surgical treatment is recommended on the basis of an individual's risk of rupture, which is predicted by AAA diameter. However, the natural history of AAA differs between patients and a reliable and individual predictor of AAA progression (growth and expansion rates) has not been established. Several circulating biomarkers are candidates for an AAA diagnostic tool. However, they have yet to meet the triad of biomarker… CONTINUE READING
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