Biomarkers in renal cell carcinoma.

  title={Biomarkers in renal cell carcinoma.},
  author={Barry B. McGuire and John M. Fitzpatrick},
  journal={Current opinion in urology},
  volume={19 5},
PURPOSE OF REVIEW To review the latest information on biomarkers in renal cell carcinoma and their use in integrated staging systems. RECENT FINDINGS The discovery of the Von Hippel-Lindau defect and the hypoxia inducible factor-1alpha transcripted genes has led to an explosion in the understanding of molecular pathways in renal cell carcinoma. The two most prominent biomarkers are carbonic anhydrase IX and vascular endothelial-derived growth factor. Carbonic anhydrase IX has demonstrated… CONTINUE READING


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