Biomarkers in experimental models of antibody-mediated neuropathies.

  title={Biomarkers in experimental models of antibody-mediated neuropathies.},
  author={Hugh John Willison},
  journal={Journal of the peripheral nervous system : JPNS},
  volume={16 Suppl 1},
Autoimmune neuropathy models have been refined in animals over the past 50 years to enable links to be made between antibody signatures and disease pathogenesis; however, the application of these models to identify biomarkers has not been fully developed. Models for chronic inflammatory demyelinating polyneuropathy (CIDP) must ensure that adequate distinctions are made from variants of other neuropathic states such as Guillain-Barré syndrome (GBS) in order to be of greatest clinical use. One of… CONTINUE READING