Biomarkers for ischemic preconditioning: finding the responders.

  title={Biomarkers for ischemic preconditioning: finding the responders.},
  author={Sebastian Koch and David Della-Morte and Kunjan R Dave and Ralph L. Sacco and Miguel A. P{\'e}rez-Pinz{\'o}n},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  volume={34 6},
Ischemic preconditioning is emerging as an innovative and novel cytoprotective strategy to counter ischemic vascular disease. At the root of the preconditioning response is the upregulation of endogenous defense systems to achieve ischemic tolerance. Identifying suitable biomarkers to show that a preconditioning response has been induced remains a translational research priority. Preconditioning leads to a widespread genomic and proteonomic response with important effects on hemostatic… CONTINUE READING