Biomarkers for intracellular pathogens: establishing tools as vaccine and therapeutic endpoints for visceral leishmaniasis.

@article{Vallur2014BiomarkersFI,
  title={Biomarkers for intracellular pathogens: establishing tools as vaccine and therapeutic endpoints for visceral leishmaniasis.},
  author={Aarthy C. Vallur and Malcolm S. Duthie and Caroline Reinhart and Yeung L. Tutterrow and Shin-ichiro Hamano and Khondaker Rifat Hasan Bhaskar and Rhea N. Coler and Dinesh Mondal and Steven G Reed},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2014},
  volume={20 6},
  pages={O374-83}
}
Visceral leishmaniasis in South Asia is a serious disease affecting children and adults. Acute visceral leishmaniasis develops in only a fraction of those infected individuals, the majority being asymptomatic with the potential to transmit infection and develop disease. We followed 56 individuals characterized as being asymptomatic by seropositivity with rk39 rapid diagnostic test in a hyperendemic district of Bangladesh to define the utility of Leishmania-specific antibodies and DNA in… CONTINUE READING

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