Biomarkers for epithelial-mesenchymal transitions.

  title={Biomarkers for epithelial-mesenchymal transitions.},
  author={Michael Zeisberg and Eric G. Neilson},
  journal={The Journal of clinical investigation},
  volume={119 6},
Somatic cells that change from one mature phenotype to another exhibit the property of plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this plasticity, which is easily demonstrated by studying the process of epithelial-mesenchymal transition (EMT). Published reports from the literature typically rely on ad hoc criteria for determining EMT events; consequently, there is some uncertainty as to whether the same process occurs under different experimental… CONTINUE READING
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