Biomarkers for early prostate cancer detection.

  title={Biomarkers for early prostate cancer detection.},
  author={Markus Margreiter and Anton Stangelberger and E Valimberti and Ralf Herwig and Bob Djavan},
  journal={Minerva urologica e nefrologica = The Italian journal of urology and nephrology},
  volume={60 1},
In the 1990s the discovery of prostate-specific antigen (PSA) revolutionized early prostate cancer detection. Since that time, PSA has become an indispensable marker for diagnosis and follow up of prostate cancer patients. Despite its remarkable performance, PSA is not cancer specific. High PSA levels are found in both cancerous and healthy tissue, particularly in benign prostate disease, resulting in significant numbers of false positive cases. Hence, there is a need for new markers that… CONTINUE READING

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