Biomarkers for early detection of colon cancer.

  title={Biomarkers for early detection of colon cancer.},
  author={Sudhir K. Srivastava and Meena Verma and Donald E. Henson},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={7 5},
There is an increasing demand for biomarkers in colon cancer for risk assessment, early detection, prognosis, and surrogate end points. A number of biomarkers have been identified for early detection of colon cancer, although the risk factors have not been identified extensively. The major advances in understanding colorectal cancer include the identification and the involvement of APC, p53, and Ki-ras in the development and progression of the disease, the identification of the aberrant crypt… CONTINUE READING


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