Biomarkers for Circadian Rhythm Disruption Independent of Time of Day

  title={Biomarkers for Circadian Rhythm Disruption Independent of Time of Day},
  author={Kirsten C. G. Van Dycke and Jeroen L. A. Pennings and Conny T. M. van Oostrom and Linda Wilhelmina Maria van Kerkhof and Harry van Steeg and Gijsbertus T. J. van der Horst and Wendy Rodenburg},
  booktitle={PloS one},
Frequent shift work causes disruption of the circadian rhythm and might on the long-term result in increased health risk. Current biomarkers evaluating the presence of circadian rhythm disturbance (CRD), including melatonin, cortisol and body temperature, require 24-hr ("around the clock") measurements, which is tedious. Therefore, these markers are not eligible to be used in large-scale (human) studies. The aim of the present study was to identify universal biomarkers for CRD independent of… CONTINUE READING
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