Biomarkers associated with diffuse traumatic axonal injury: exploring pathogenesis, early diagnosis, and prognosis.

@article{Li2010BiomarkersAW,
  title={Biomarkers associated with diffuse traumatic axonal injury: exploring pathogenesis, early diagnosis, and prognosis.},
  author={Jia Li and Xue-Yuan Li and Dong-Fu Feng and Dong-Chao Pan},
  journal={The Journal of trauma},
  year={2010},
  volume={69 6},
  pages={1610-8}
}
BACKGROUND Diffuse traumatic axonal injury (dTAI) is a significant pathologic feature of traumatic brain injury and is associated with substantial mortality and morbidity. It is still a challenge for clinicians to make an early diagnosis of dTAI and generate accurate prognosis and direct therapeutic decisions because most patients rapidly progress to coma after trauma and because specific neurologic symptoms and focal lesions detectable with current routine imaging techniques are absent. To… CONTINUE READING

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