Biomarkers and Stimulation Algorithms for Adaptive Brain Stimulation

  title={Biomarkers and Stimulation Algorithms for Adaptive Brain Stimulation},
  author={Kimberly B. Hoang and Isaac R. Cassar and Warren M. Grill and Dennis A. Turner},
  journal={Frontiers in Neuroscience},
The goal of this review is to describe in what ways feedback or adaptive stimulation may be delivered and adjusted based on relevant biomarkers. Specific treatment mechanisms underlying therapeutic brain stimulation remain unclear, in spite of the demonstrated efficacy in a number of nervous system diseases. Brain stimulation appears to exert widespread influence over specific neural networks that are relevant to specific disease entities. In awake patients, activation or suppression of these… 

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