Biomarker discovery in urine by proteomics.

@article{Pang2002BiomarkerDI,
  title={Biomarker discovery in urine by proteomics.},
  author={James X Pang and Nicole Ginanni and Ashok R. Dongr{\'e} and Stanley A. Hefta and Gregory J Opitek},
  journal={Journal of proteome research},
  year={2002},
  volume={1 2},
  pages={161-9}
}
A hypothesis was formed that it would be possible to isolate an adequate amount of protein from a patient, having normal renal function, to identify biological markers of a particular disease state using a variety of proteomics techniques. To support this hypothesis, three samples of urine were collected from a volunteer: first when healthy, later when experiencing acute inflammation due to a pilonidal abcess, and again later still after successful recovery from the condition. The urine from… CONTINUE READING

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