Biomarker discovery from uveal melanoma secretomes: identification of gp100 and cathepsin D in patient serum.


There is a necessity to better characterize uveal melanoma (UM) tumors according to their metastasis potential at an early stage. In this study we report the identification of potential biomarkers by a combination of proteomics-related approaches: the characterization of UM cell secretomes, the analysis of UM autoantibodies, and the differential depleted… (More)