Bioluminescence imaging of the response of rat gliosarcoma to ALA-PpIX-mediated photodynamic therapy.

Abstract

Photodynamic therapy (PDT) is a promising modality for the treatment of solid tumors that combines a photosensitizing agent and light to produce cytotoxic reactive oxygen species that lead to tumor cell death. The recent introduction of bioluminescence imaging (BLI), involving the use of the luciferase gene (luc) transferred into target tumor cells… (More)

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@article{Moriyama2004BioluminescenceIO, title={Bioluminescence imaging of the response of rat gliosarcoma to ALA-PpIX-mediated photodynamic therapy.}, author={Eduardo H. Moriyama and Stuart K. Bisland and Lothar Lilge and Brian C. Wilson}, journal={Photochemistry and photobiology}, year={2004}, volume={80 2}, pages={242-9} }