Biology of human sodium glucose transporters.
@article{Wright2011BiologyOH,
title={Biology of human sodium glucose transporters.},
author={Ernest M. Wright and Donald D. F. Loo and Bruce A. Hirayama},
journal={Physiological reviews},
year={2011},
volume={91 2},
pages={
733-94
}
}There are two classes of glucose transporters involved in glucose homeostasis in the body, the facilitated transporters or uniporters (GLUTs) and the active transporters or symporters (SGLTs). The energy for active glucose transport is provided by the sodium gradient across the cell membrane, the Na(+) glucose cotransport hypothesis first proposed in 1960 by Crane. Since the cloning of SGLT1 in 1987, there have been advances in the genetics, molecular biology, biochemistry, biophysics, and…
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