Biology of developmental and regenerative skeletogenesis.

@article{Tuan2004BiologyOD,
  title={Biology of developmental and regenerative skeletogenesis.},
  author={Rocky S. Tuan},
  journal={Clinical orthopaedics and related research},
  year={2004},
  volume={427 Suppl},
  pages={
          S105-17
        }
}
Embryonic skeletal development involves the recruitment, commitment, differentiation, and maturation of mesenchymal cells into those in the skeletal tissue lineage, specifically cartilage and bone along the intramembranous and endochondral ossification pathways. The exquisite control of skeletal development is regulated at the level of gene transcription, cellular signaling, cell-cell and cell-matrix interactions, as well as systemic modulation. Mediators include transcription factors, growth… CONTINUE READING

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