Biology of Human Tumors To " Grow " or " Go " : TMEM 16 A Expression as a Switch between Tumor Growth and Metastasis in SCCHN

Abstract

Purpose: Tumor metastasis is the leading cause of death in patients with cancer. However, the mechanisms that underlie metastatic progression remain unclear. We examined TMEM16A (ANO1) expression as a key factor shifting tumors between growth and metastasis. Experimental Design: We evaluated 26 pairs of primary and metastatic lymph node (LN) tissue from… (More)

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