Biology and Treatment of Rhabdoid Tumor.

  title={Biology and Treatment of Rhabdoid Tumor.},
  author={James I Geller and Jacquelyn J. Roth and Jaclyn A Biegel},
  journal={Critical reviews in oncogenesis},
  volume={20 3-4},
Rhabdoid tumor is a rare, highly aggressive malignancy that primarily affects infants and young children. These tumors typically arise in the brain and kidney, although extrarenal, non-central nervous system tumors in almost all soft-tissue sites have been described. SMARCB1 is a member of the SWI/SNF chromatin-remodeling complex and functions as a tumor… CONTINUE READING