Biologics-based therapy for the treatment of rheumatoid arthritis.

@article{Scott2012BiologicsbasedTF,
  title={Biologics-based therapy for the treatment of rheumatoid arthritis.},
  author={David Lloyd Scott},
  journal={Clinical pharmacology and therapeutics},
  year={2012},
  volume={91 1},
  pages={30-43}
}
Rheumatoid arthritis (RA) remains a major clinical problem, but treatments involving biologics have revolutionized its management. They target pathogenically relevant cytokines such as tumor necrosis factor and immune cells such as B cells. In RA, biologics reduce joint inflammation, limit erosive damage, decrease disability, and improve quality of life. Infections are the main risk associated with their use. Because of the high prices of biologics, their cost-effectiveness is a matter of… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 7 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 64 extracted citations

Immunogenicity of anti-tumour necrosis factor drugs in rheumatic diseases.

Clinical and experimental rheumatology • 2013
View 8 Excerpts
Highly Influenced

Taurine and inflammatory diseases

Amino Acids • 2012
View 3 Excerpts
Highly Influenced

Osteonecrosis of the Jaw in the Absence of Antiresorptive or Antiangiogenic Exposure: A Series of 6 Cases.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons • 2017

References

Publications referenced by this paper.
Showing 1-10 of 109 references

Abatacept therapy and safety management.

Joint, bone, spine : revue du rhumatisme • 2012

Similar Papers

Loading similar papers…