Biologically active derivatives of fatty acids: prostaglandins, thromboxanes, and endoperoxides.

Abstract

The causal role assigned to the E and F prostaglandins in inflammatory processes, implied by the antiinflammatory action of prostaglandin synthetase inhibitors, is not consistent with the findings reported here that a compound (MK-447) capable of increasing levels of these prostaglandins is antiinflammatory in classical animal models of acute inflammation… (More)

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@article{Kuehl1977BiologicallyAD, title={Biologically active derivatives of fatty acids: prostaglandins, thromboxanes, and endoperoxides.}, author={Frederick A. Kuehl and John L Humes and Gayle Beveridge and C G van Arman and Robert W. Egan}, journal={Inflammation}, year={1977}, volume={2 4}, pages={285-94} }