Biological voyage of solid lipid nanoparticles: a proficient carrier in nanomedicine.

  title={Biological voyage of solid lipid nanoparticles: a proficient carrier in nanomedicine.},
  author={H. Ali and S. Singh},
  journal={Therapeutic delivery},
  volume={7 10},
  • H. Ali, S. Singh
  • Published 2016
  • Materials Science, Medicine
  • Therapeutic delivery
This review projects the prospects and issues faced by solid lipid nanoparticles (SLNs) in current scenarios, specially related to its clinical implementation and effectiveness. We re-examine the basic concept of biobehavior and movement of SLNs as a nanomedicine carrier. The extensive survey of the uptake and absorption mechanism from different routes, distribution pattern, targeting efficiency, effect of surface functionalization on biodistribution, elimination pathways and toxic effects have… Expand
11 Citations
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In this work, we conducted pharmacokinetic studies and established the in vitro and in vivo correlation (IVIVC) of furosemide (FRS) loaded solid lipid nanoparticles (FSLN). A bioanalytical methodExpand


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Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives
  • M. Üner, G. Yener
  • Materials Science, Medicine
  • International journal of nanomedicine
  • 2007
Solid lipid nanoparticles (SLN) have been reported to be an alternative system to emulsions, liposomes, microparticles and their polymeric counterparts for various application routes since the earlyExpand
The use of solid lipid nanoparticles to target a lipophilic molecule to the liver after intravenous administration to mice.
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Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles.
  • D. Peer
  • Biology, Medicine
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