Biological variation of cardiac markers: analytical and clinical considerations.


The analytical, within-subject and between-subject components of variation were estimated for serum total creatine kinase (TCK) activity, CK-MB (creatine kinase-MB) activity, CK-MB mass, ratios of CK-MB activity and CK-MB mass to TCK activity and myoglobin concentration in a cohort of 16 apparently healthy subjects over 5 days. Analytical goals based on… (More)


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