Biological synthesis of cholesterol.
@article{Bloch1952BiologicalSO, title={Biological synthesis of cholesterol.}, author={K. Bloch}, journal={Harvey lectures}, year={1952}, volume={48}, pages={ 68-88 } }
Publisher Summary This chapter examines cholesterol metabolism in terms of the molecular events that are responsible for constructing cyclopentanoperhydrophenanthrene derivatives from small molecular precursors. There is good reason for centering a discussion of steroid biogenesis around cholesterol, not only because this substance has received the major share of attention but also because cholesterol synthesis appears to be an integral part of the processes leading to the physiologically… CONTINUE READING
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References
SHOWING 1-10 OF 55 REFERENCES
The utilization of squalene in the biosynthesis of cholesterol.
- Biology, Medicine
- The Journal of biological chemistry
- 1953
- 68
- PDF
STUDIES ON THE UTILIZATION OF ACETIC ACID FOR THE BIOLOGICAL SYNTHESIS OF CHOLESTEROL
- Chemistry
- 1950
- 62
- PDF
Squalene as a precursor of cholesterol in liver.
- Medicine, Chemistry
- The Journal of biological chemistry
- 1953
- 11
- PDF
Studies on the utilization of isovaleric acid in cholesterol synthesis.
- Medicine, Biology
- The Journal of biological chemistry
- 1951
- 16
- PDF
Synthesis of cholesterol in surviving liver.
- Medicine, Biology
- The Journal of biological chemistry
- 1946
- 99
- PDF
Studies on the biosynthesis of cholesterol. VI. Companions of cholesterol-C14 in liver perfusions, including squalene-C14 as possible precursors in its biosynthesis.
- Chemistry, Medicine
- Archives of biochemistry and biophysics
- 1954
- 16
Isotopic acetate and isovalerate in the synthesis of ergosterol by Neurospora.
- Medicine, Biology
- The Journal of biological chemistry
- 1951
- 32
- PDF
The Metabolism of Isoprenoid Precursors in a Plant System.
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1954
- 21
- PDF
Biosynthesis of squalene and cholesterol in vitro from acetate-1-C14.
- Biology, Medicine
- Archives of biochemistry and biophysics
- 1954
- 29
The steroid requirements of Labyrinthula vitellina var. pacifica.
- Biology, Medicine
- Journal of general microbiology
- 1953
- 32
- PDF