Biological significance of soluble IL-2 receptor

@article{Caruso1993BiologicalSO,
  title={Biological significance of soluble IL-2 receptor},
  author={C. Caruso and G. Candore and D. Cigna and A. T. Colucci and M. A. Modica},
  journal={Mediators of Inflammation},
  year={1993},
  volume={2},
  pages={3 - 21}
}
  • C. Caruso, G. Candore, +2 authors M. A. Modica
  • Published 1993
  • Medicine
  • Mediators of Inflammation
  • A NUMBER of receptors for growth factors and differentiation antigens have been found to be secreted or released by cells. Following mononuclear cell (MNC) activation and interleukin-2 receptor (IL-2R) expression, a soluble form of the Alpha;-chain of IL-2R (sIL-2R) is released. The sIL-2R has been shown to be present in the culture supernatants of activated MNCs as well as in normal sera and, in higher amounts, in sera from subjects affected by several diseases including neoplastic, infectious… CONTINUE READING
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