Biological significance of chromosomal imbalance aberrations in gastrointestinal stromal tumors.

@article{Chen2004BiologicalSO,
  title={Biological significance of chromosomal imbalance aberrations in gastrointestinal stromal tumors.},
  author={Yi Chen and C. Tzeng and Chiou-Ping Liou and Ming-Yu Chang and C. Li and Ching-Nan Lin},
  journal={Journal of biomedical science},
  year={2004},
  volume={11 1},
  pages={65-71}
}
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Current criteria for the diagnosis of malignant GISTs do not always reliably predict patient outcomes. In order to search for genetic markers with prognostic potential, chromosomal imbalance aberrations (CIAs) were analyzed in 28 subjects with GIST using comparative genomic hybridization and correlated with clinicopathological features. Except for a small rectal tumor, CIAs were… CONTINUE READING
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