• DOI:10.1023/B:GLYC.0000043749.06556.3d
Corpus ID: 2678053

Biological roles of sulfoglycolipids and pathophysiology of their deficiency

@article{Honke2004BiologicalRO,
  title={Biological roles of sulfoglycolipids and pathophysiology of their deficiency},
  author={K. Honke and Yanglong Zhang and X. Cheng and N. Kotani and N. Taniguchi},
  journal={Glycoconjugate Journal},
  year={2004},
  volume={21},
  pages={59-62}
}

K. Honke, Yanglong Zhang, +2 authors N. Taniguchi

Published 2004

Biology, Medicine

Glycoconjugate Journal

Mammalian sulfoglycolipids are comprised of two major members, sulfatide (SO3-3Gal-ceramide) and seminolipid (SO3-3Gal-alkylacylglycerol). Sulfatide is abundant in the myelin sheath and seminolipid is expressed on the spermatogenic cells. Cerebroside sulfotransferase (CST)-deficient mice generated by gene targeting completely lack sulfatide and seminolipid all over the body. CST-null mice manifest some neurological disorders due to myelin dysfunction, an aberrant enhancement of oligodendrocyte… CONTINUE READING

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