Biological roles of sulfoglycolipids and pathophysiology of their deficiency
@article{Honke2004BiologicalRO, title={Biological roles of sulfoglycolipids and pathophysiology of their deficiency}, author={K. Honke and Yanglong Zhang and X. Cheng and N. Kotani and N. Taniguchi}, journal={Glycoconjugate Journal}, year={2004}, volume={21}, pages={59-62} }
Mammalian sulfoglycolipids are comprised of two major members, sulfatide (SO3-3Gal-ceramide) and seminolipid (SO3-3Gal-alkylacylglycerol). Sulfatide is abundant in the myelin sheath and seminolipid is expressed on the spermatogenic cells. Cerebroside sulfotransferase (CST)-deficient mice generated by gene targeting completely lack sulfatide and seminolipid all over the body. CST-null mice manifest some neurological disorders due to myelin dysfunction, an aberrant enhancement of oligodendrocyte… CONTINUE READING
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References
SHOWING 1-10 OF 21 REFERENCES
Paranodal junction formation and spermatogenesis require sulfoglycolipids
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 2002
- 285
- PDF
Sulfatide is a negative regulator of oligodendrocyte differentiation: Development in sulfatide‐null mice
- Biology, Medicine
- Glia
- 2004
- 86
Requirement of Seminolipid in Spermatogenesis Revealed by UDP-galactose:Ceramide Galactosyltransferase-deficient Mice*
- Biology, Medicine
- The Journal of Biological Chemistry
- 2000
- 103
- PDF
Myelination in the Absence of Galactocerebroside and Sulfatide: Normal Structure with Abnormal Function and Regional Instability
- Biology, Medicine
- Cell
- 1996
- 544
- PDF
Myelin Galactolipids Are Essential for Proper Node of Ranvier Formation in the CNS
- Chemistry, Medicine
- The Journal of Neuroscience
- 1998
- 218
- PDF
Cerebroside Sulfotransferase Deficiency Ameliorates L-selectin-dependent Monocyte Infiltration in the Kidney after Ureteral Obstruction*
- Chemistry, Medicine
- Journal of Biological Chemistry
- 2004
- 43
- PDF
Negative Regulation of Oligodendrocyte Differentiation by Galactosphingolipids
- Biology, Medicine
- The Journal of Neuroscience
- 1999
- 106
- PDF
A Myelin Galactolipid, Sulfatide, Is Essential for Maintenance of Ion Channels on Myelinated Axon But Not Essential for Initial Cluster Formation
- Chemistry, Medicine
- The Journal of Neuroscience
- 2002
- 221
- PDF
Ceramide UDPgalactosyltransferase from myelinating rat brain: purification, cloning, and expression.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1993
- 154
- PDF
cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase.
- Biology, Medicine
- European journal of biochemistry
- 2000
- 54