Biological roles of lysophospholipid receptors revealed by genetic null mice: an update.

@article{Choi2008BiologicalRO,
  title={Biological roles of lysophospholipid receptors revealed by genetic null mice: an update.},
  author={Ji Woong Choi and Chang-Wook Lee and Jerold Chun},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1781 9},
  pages={
          531-9
        }
}
  • Ji Woong Choi, Chang-Wook Lee, Jerold Chun
  • Published 2008
  • Biology, Medicine
  • Biochimica et biophysica acta
  • Two lysophospholipids (LPs), lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), are known to affect various cellular events. Their actions are mediated by binding to at least ten bona fide high-affinity G protein-coupled receptors referred to as LPA1-5 and S1P1-5. These LPs are expressed throughout the body and are involved in a range of biological activities including normal development, as well as functioning in most organ systems. A growing number of biological functions have… CONTINUE READING

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