Biological role of p300 in cardiac myocytes


A cellular target of adenovirus E1A oncoprotein, p300 is a transcriptional coactivator required for the maintenance of differentiated phenotypes in cardiac myocytes. The full transcriptional activities of hypertrophy-responsive transcription factors such as GATA-4 and MEF2 require interaction with p300. A p300 protein also possesses intrinsic histone acetyl… (More)
DOI: 10.1023/A:1024132217870

2 Figures and Tables


  • Presentations referencing similar topics