Biological regulation of bone quality.

@article{Alliston2014BiologicalRO,
  title={Biological regulation of bone quality.},
  author={Tamara Alliston},
  journal={Current osteoporosis reports},
  year={2014},
  volume={12 3},
  pages={
          366-75
        }
}
The ability of bone to resist fracture is determined by the combination of bone mass and bone quality. Like bone mass, bone quality is carefully regulated. Of the many aspects of bone quality, this review focuses on biological mechanisms that control the material quality of the bone extracellular matrix (ECM). Bone ECM quality depends upon ECM composition and organization. Proteins and signaling pathways that affect the mineral or organic constituents of bone ECM impact bone ECM material… CONTINUE READING
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