Biological production of monoethanolamine by engineered Pseudomonas putida S12.

@article{Foti2013BiologicalPO,
  title={Biological production of monoethanolamine by engineered Pseudomonas putida S12.},
  author={Mirjam J. Foti and Rosario M{\'e}dici and Harald J. Ruijssenaars},
  journal={Journal of biotechnology},
  year={2013},
  volume={167 3},
  pages={344-9}
}
Pseudomonas putida S12 was engineered for the production of monoethanolamine (MEA) from glucose via the decarboxylation of the central metabolite L-serine, which is catalyzed by the enzyme L-serine decarboxylase (SDC). The host was first evaluated for its tolerance towards MEA as well as its endogenous ability to degrade this alkanolamine. Growth inhibition was observed at MEA concentrations above 100 mM, but growth was never completely arrested even at 750 mM of MEA. P. putida S12 was able to… CONTINUE READING

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