Biological predictors of radiosensitivity in head and neck squamous cell carcinoma

@article{Fiedler2017BiologicalPO,
  title={Biological predictors of radiosensitivity in head and neck squamous cell carcinoma},
  author={Mathias Fiedler and F. Weber and Matthias G{\"u}nther Hautmann and Frank Haubner and Torsten Eugen Reichert and Christoph Klingelh{\"o}ffer and Stephan Schreml and J K Meier and Arndt Hartmann and Tobias Ettl},
  journal={Clinical Oral Investigations},
  year={2017},
  volume={22},
  pages={189-200}
}
ObjectivesThe aim of this study is to investigate the influence of prognostic biomarkers on radiosensitivity and survival of advanced head and neck squamous cell carcinomas treated by primary (chemo)radiation.Material and methodsThe clinicopathological data and immunohistochemical staining of p16, c-Met, survivin, PD-1, and PD-L1 of 82 primarily (chemo)irradiated patients with head and neck squamous cell carcinoma were analyzed. Associations with local and locoregional radiation response… CONTINUE READING

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