Biological markers of Pseudomonas aeruginosa epidemic high-risk clones.

  title={Biological markers of Pseudomonas aeruginosa epidemic high-risk clones.},
  author={Xavier Mulet and Gabriel Cabot and Alain Antonio Ocampo-Sosa and Maria {\'A}ngeles Dom{\'i}nguez and Laura Zamorano and Carlos Juan and F{\'e} Tubau and Cristina Rodr{\'i}guez and Bartolome Moya and Carmen Pe{\~n}a and Luis Horacio Mart{\'i}nez-Mart{\'i}nez and Antonio Oliver},
  journal={Antimicrobial agents and chemotherapy},
  volume={57 11},
A limited number of Pseudomonas aeruginosa genotypes (mainly ST-111, ST-175, and ST-235), known as high-risk clones, are responsible for epidemics of nosocomial infections by multidrug-resistant (MDR) or extensively drug-resistant (XDR) strains worldwide. We explored the potential biological parameters that may explain the success of these clones. A total of 20 isolates from each of 4 resistance groups (XDR, MDR, ModR [resistant to 1 or 2 classes], and MultiS [susceptible to all… CONTINUE READING
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