Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair.

Abstract

We develop a novel mathematical model for collagen deposition and alignment during dermal wound healing. We focus on the interactions between fibroblasts, modelled as discrete entities, and a continuous extracellular matrix composed of collagen and a fibrin based blood clot. There are four basic interactions assumed in the model: fibroblasts orient the… (More)

Topics

2 Figures and Tables

Slides referencing similar topics