Biological impact of hepatitis B virus X-hepatitis C virus core fusion gene on human hepatocytes.

@article{Ma2008BiologicalIO,
  title={Biological impact of hepatitis B virus X-hepatitis C virus core fusion gene on human hepatocytes.},
  author={Zhen Lei Ma and Qin-Hai Shen and Guo-min Chen and Da-zhi Zhang},
  journal={World journal of gastroenterology},
  year={2008},
  volume={14 35},
  pages={
          5412-8
        }
}
AIM To investigate the biological impact of hepatitis B virus X- hepatitis C virus core (HBV X-HCV C) fusion gene on hepatoma cells. METHODS The recombinant adenoviruses Ad-XC, Ad-X and Ad-C expressing HBV X-HCV C fusion gene, HBV X gene and HCV C gene were constructed, respectively. Hepatoma cells were infected with different recombinant adenoviruses. MTT, colony-forming experiment, FCM, TUNEL assay were performed to observe the biological impact of the HBV X-HCV C fusion gene on liver cells… CONTINUE READING
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