Biological half-time and body burden of cadmium in dogs after a long-term oral administration of cadmium

@article{Matsuno1991BiologicalHA,
  title={Biological half-time and body burden of cadmium in dogs after a long-term oral administration of cadmium},
  author={Koji Matsuno and Yasushi Kodama and Kenzaburo Tsuchiya},
  journal={Biological Trace Element Research},
  year={1991},
  volume={29},
  pages={111-123}
}
To investigate the kinetic behavior of cadmium, we conducted a long-term oral administration experiment, using beagle dogs. The experimental animals were given a commercial diet and pelleted food containing 1, 3, 10, 50, and 100 mg of cadmium per day in the form of cadmium chloride for 8 yr. A single injection of cadmium (as CdCl2) into dogs was also performed in order to obtain fundamental kinetic information for a dog. The kinetic behavior of cadmium in chronic experiment is described… CONTINUE READING