Biological functions of sphingomyelins.

@article{Slotte2013BiologicalFO,
  title={Biological functions of sphingomyelins.},
  author={J Peter Slotte},
  journal={Progress in lipid research},
  year={2013},
  volume={52 4},
  pages={424-37}
}
Sphingomyelin (SM) is a dominant sphingolipid in membranes of mammalian cells and this lipid class is specifically enriched in the plasma membrane, the endocytic recycling compartment, and the trans Golgi network. The distribution of SM and cholesterol among cellular compartments correlate. Sphingolipids have extensive hydrogen-bonding capabilities which together with their saturated nature facilitate the formation of sphingolipid and SM-enriched lateral domains in membranes. Cholesterol… CONTINUE READING

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