Biological function of metallothionein. V. Its induction in rats by various stresses.

@article{Oh1978BiologicalFO,
  title={Biological function of metallothionein. V. Its induction in rats by various stresses.},
  author={Seung Hun Oh and J. T. Deagen and Philip DY Whanger and P H Weswig},
  journal={The American journal of physiology},
  year={1978},
  volume={234 3},
  pages={E282-5}
}
Induction of metallothionein (a Zn-binding protein) was investigated in liver and kidneys of rats under the following stresses: cold environment, hot environment, heat burn, strenuous exercise, and CCl4 intoxication. As markers of metallothionein (MT) synthesis, [14C]cystine and 65Zn were injected parenterally into rats, and MT in liver and kidney supernatants was separated on Sephadex G-75 columns. Among stresses tested, the greatest stimulations of MT synthesis in liver were observed under… CONTINUE READING

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