Biological fate of tissue-engineered porcine valvular conduits xenotransplanted in the sheep thoracic aorta.


The ideal prosthesis to replace the diseased human aortic valve is not yet available. We have previously shown that porcine acellular aortic-valve conduits, obtained by detergent-enzymatic method, display hemodynamic performances similar to those of their native counterparts. Hence, it seemed worthwhile to ascertain whether these tissue-engineered… (More)


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