Biological factors influencing the RBE of neutrons: implications for their past, present and future use in radiotherapy.

@article{Britten2001BiologicalFI,
  title={Biological factors influencing the RBE of neutrons: implications for their past, present and future use in radiotherapy.},
  author={Richard A. Britten and L. J. Peters and David C. Murray},
  journal={Radiation research},
  year={2001},
  volume={156 2},
  pages={125-35}
}
The recent resurgence of interest in fast-neutron therapy, particularly for the treatment of prostate cancer, warrants a review of the original radiobiological basis for this modality and the evolution of these concepts that resulted from subsequent experimentation with the fast-neutron beams used for randomized clinical trials. It is clear from current radiobiological knowledge that some of the postulates that formed the mechanistic basis for past clinical trials were incorrect. Such… CONTINUE READING

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