Biological evidence of genetic exchange in Entamoeba histolytica.

  title={Biological evidence of genetic exchange in Entamoeba histolytica.},
  author={P. G. Sargeaunt and Terry F H G Jackson and S R Wiffen and R Bhojnani},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  volume={82 6},
The demonstration of a new zymodeme of Entamoeba histolytica produced in culture from cloned isolates suggested possible genetic exchange in this parasite. We have attempted to substantiate that finding by using rats as biological hosts. Clones were made from 3 separate isolates of E. histolytica, each established in culture from liver pus or faeces. After enzyme characterization these clones, of zymodemes II, XIV and XIX, were paired in each of the 3 possible combinations and the mixtures… CONTINUE READING