Biological effects of ultrasound exposure on adriamycin-resistant and cisplatin-resistant human ovarian carcinoma cell lines in vitro.

Human ovarian cancer cell lines, SKOV3 and its adriamycin-resistant substrain SKOV3/ADR and COC1 and its cisplatin-resistant substrain COC1/DDP, were subjected to acoustic exposure. The critical levels (LC), which resulted in no immediate cell killing, were determined in four cell lines, respectively. LC were the same in four cell lines. After being… CONTINUE READING