Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms.

@article{AlLahham2010BiologicalEO,
  title={Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms.},
  author={Sa'ad H. Al-Lahham and Maikel P Peppelenbosch and H. W. Roelofsen and Roel J Vonk and K Venema},
  journal={Biochimica et biophysica acta},
  year={2010},
  volume={1801 11},
  pages={1175-83}
}
Undigested food is fermented in the colon by the microbiota and gives rise to various microbial metabolites. Short-chain fatty acids (SCFA), including acetic, propionic and butyric acid, are the principal metabolites produced. However, most of the literature focuses on butyrate and to a lesser extent on acetate; consequently, potential effects of propionic acid (PA) on physiology and pathology have long been underestimated. It has been demonstrated that PA lowers fatty acids content in liver… CONTINUE READING
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